Dual Role of Dietary Curcumin Through Attenuating AFB(1)-Induced Oxidative Stress and Liver Injury via Modulating Liver Phase-I and Phase-II Enzymes Involved in AFB(1) Bioactivation and Detoxification

It is well understood that liver cytochrome p450 enzymes are responsible for AFB(1) bioactivation, while phase-II enzymes regulated by the transcription factor nuclear factor-erythroid-2-related factor 2 (Nrf2) are involved in detoxification of AFB(1). In this study, we explored the potential of cur...

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Detalles Bibliográficos
Autores principales: Muhammad, Ishfaq, Wang, He, Sun, Xiaoqi, Wang, Xinghe, Han, Meiyu, Lu, Ziyin, Cheng, Ping, Hussain, Muhammad A., Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981209/
https://www.ncbi.nlm.nih.gov/pubmed/29887802
http://dx.doi.org/10.3389/fphar.2018.00554

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