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Resting T cells are hypersensitive to DNA damage due to defective DNA repair pathway

Blood cells are challenged by intrinsic and exogenous stress that may result in many types of damage to DNA. As a major participant in cell-mediated immunity in blood, T lymphocytes are maintained in their quiescent (resting) state for most of their lives and switch to the proliferating state once s...

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Detalles Bibliográficos
Autores principales: Hu, Qian, Xie, Yujie, Ge, Yuanlong, Nie, Xin, Tao, Jun, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981309/
https://www.ncbi.nlm.nih.gov/pubmed/29855463
http://dx.doi.org/10.1038/s41419-018-0649-z

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