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Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish
Activation of hepatic stellate cells (HSC) plays a crucial role in the liver disease progression from liver fibrosis/cirrhosis to cancer. Here, we found a rapid change of microenvironment after kras(V12)-induction in zebrafish liver with progressively increased stromal cell number and enlarged liver...
Autores principales: | Yang, Qiqi, Yan, Chuan, Gong, Zhiyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981472/ https://www.ncbi.nlm.nih.gov/pubmed/29855567 http://dx.doi.org/10.1038/s41598-018-26612-0 |
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