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Relationship between KCNQ1 (LQT1) and KCNH2 (LQT2) gene mutations and sudden death during illegal drug use
Long QT syndrome (LQTS), a congenital genetic disorder, can cause torsades de pointes (TdP), and lethal cardiac arrhythmia may result from ingestion of cardiotoxic drugs. Methamphetamine (MP) and new psychoactive substances (NPSs) can trigger TdP due to QT prolongation, leading to sudden death. We t...
Autores principales: | Nagasawa, Sayaka, Saitoh, Hisako, Kasahara, Shiori, Chiba, Fumiko, Torimitsu, Suguru, Abe, Hiroko, Yajima, Daisuke, Iwase, Hirotaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981596/ https://www.ncbi.nlm.nih.gov/pubmed/29855564 http://dx.doi.org/10.1038/s41598-018-26723-8 |
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