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HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases. The acquisition of invasive and pro-fibrotic abilities by mesothelial cells (MCs) through induction o...

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Detalles Bibliográficos
Autores principales: Rossi, Lucia, Battistelli, Cecilia, de Turris, Valeria, Noce, Valeria, Zwergel, Clemens, Valente, Sergio, Moioli, Alessandra, Manzione, Andrea, Palladino, Marco, Bordoni, Veronica, Domenici, Alessandro, Menè, Paolo, Mai, Antonello, Tripodi, Marco, Strippoli, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981641/
https://www.ncbi.nlm.nih.gov/pubmed/29855565
http://dx.doi.org/10.1038/s41598-018-26319-2