Cargando…

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases. The acquisition of invasive and pro-fibrotic abilities by mesothelial cells (MCs) through induction o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rossi, Lucia, Battistelli, Cecilia, de Turris, Valeria, Noce, Valeria, Zwergel, Clemens, Valente, Sergio, Moioli, Alessandra, Manzione, Andrea, Palladino, Marco, Bordoni, Veronica, Domenici, Alessandro, Menè, Paolo, Mai, Antonello, Tripodi, Marco, Strippoli, Raffaele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981641/ https://www.ncbi.nlm.nih.gov/pubmed/29855565 http://dx.doi.org/10.1038/s41598-018-26319-2

Ejemplares similares

Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
por: Bontempi, Giulio, et al.
Publicado: (2022)

TGFβ Impairs HNF1α Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases
por: Bisceglia, Francesca, et al.
Publicado: (2019)

MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial–mesenchymal transition (MMT) of human peritoneal mesothelial cells
por: Kimura, Yuki, et al.
Publicado: (2022)

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation
por: Noce, Valeria, et al.
Publicado: (2019)

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis
por: Strippoli, Raffaele, et al.
Publicado: (2016)

Exposure to b-LED Light While Exerting Antimicrobial Activity on Gram-Negative and -Positive Bacteria Promotes Transient EMT-like Changes and Growth Arrest in Keratinocytes
por: Terri, Michela, et al.
Publicado: (2022)

Principles of MMT
por: George, Sanju, et al.
Publicado: (2009)

Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
por: Zwergel, Clemens, et al.
Publicado: (2023)

Pleural Mesothelial Cells Modulate the Inflammatory/Profibrotic Response During SARS-CoV-2 Infection
por: Matusali, Giulia, et al.
Publicado: (2021)

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis
por: Strippoli, Raffaele, et al.
Publicado: (2020)

Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation
por: Zwergel, Clemens, et al.
Publicado: (2020)

Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
por: Di Bello, Elisabetta, et al.
Publicado: (2022)

The class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells
por: Franci, Gianluigi, et al.
Publicado: (2013)

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity
por: Ippolito, Francesca, et al.
Publicado: (2023)

Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes
por: Cozzolino, Angela Maria, et al.
Publicado: (2016)

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
por: Zwergel, Clemens, et al.
Publicado: (2019)

Correction: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
por: Zwergel, Clemens, et al.
Publicado: (2022)

Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
por: Mazzone, Roberta, et al.
Publicado: (2017)

The Innovative Potential of Statins in Cancer: New Targets for New Therapies
por: Di Bello, Elisabetta, et al.
Publicado: (2020)

MMT of HIV positive patients in Georgia
por: Todadze, Khatuna, et al.
Publicado: (2012)

HCV and HIV Infection among Heroin Addicts in Methadone Maintenance Treatment (MMT) and Not in MMT in Changsha and Wuhan, China
por: Wang, Xuyi, et al.
Publicado: (2012)

Polycomb Repressive Complex 2 Modulation through the Development of EZH2–EED Interaction Inhibitors and EED Binders
por: Tomassi, Stefano, et al.
Publicado: (2021)

Editorial: New Approaches to Tackle EMT and Fibrosis: From Epigenetics to Nanotechnology
por: Battistelli, Cecilia, et al.
Publicado: (2021)

Application of Small Epigenetic Modulators in Pediatric Medulloblastoma
por: Zwergel, Clemens, et al.
Publicado: (2018)

HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells
por: Yar Saglam, Atiye Seda, et al.
Publicado: (2016)

Targeting of polycombs to DNA in EMT
por: Battistelli, Cecilia, et al.
Publicado: (2017)

A novel RNA-based approach to counteract EMT
por: Garbo, Sabrina, et al.
Publicado: (2021)

lncRNA HOTAIR functions and therapeutic perspectives
por: Garbo, Sabrina, et al.
Publicado: (2022)

Effects of treatment status and life quality on anxiety in MMT patients
por: Cao, Penghui, et al.
Publicado: (2021)

The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats
por: Jeanblanc, Jerome, et al.
Publicado: (2015)

The emerging role of epigenetics in human autoimmune disorders
por: Mazzone, Roberta, et al.
Publicado: (2019)

The Class I HDAC Inhibitor, MS-275, Prevents Oxaliplatin-Induced Chronic Neuropathy and Potentiates Its Antiproliferative Activity in Mice
por: Lamoine, Sylvain, et al.
Publicado: (2021)

Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes
por: Nebbioso, Angela, et al.
Publicado: (2009)

Stiff and tough PDMS-MMT layered nanocomposites visualized by AIE luminogens
por: Peng, Jingsong, et al.
Publicado: (2021)

Preparation and Characterization of TCPP-CaMMT Nanocompound and Its Composite with Polypropylene
por: Geng, Junming, et al.
Publicado: (2022)

HDAC Inhibitor Abrogates LTA−Induced PAI-1 Expression in Pleural Mesothelial Cells and Attenuates Experimental Pleural Fibrosis
por: Chen, Wei-Lin, et al.
Publicado: (2021)

Next RNA Therapeutics: The Mine of Non-Coding
por: Garbo, Sabrina, et al.
Publicado: (2022)

Health Tract, No. 275: Dentistry
Publicado: (1867)

SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells
por: Riccioni, Veronica, et al.
Publicado: (2022)

MS275 as Class I HDAC inhibitor displayed therapeutic potential on malignant ascites by iTRAQ-based quantitative proteomic analysis
por: Du, Li, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sjjbn0u0fuuk2edlsbb5k366qu