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Multiple roles of aryloxide leaving groups in enantioselective annulations employing α,β-unsaturated acyl ammonium catalysis

An isothiourea-catalysed Michael addition–annulation process using β-fluoroalkyl-substituted α,β-unsaturated aryl esters and a range of 2-acylbenzazoles is reported for the enantioselective synthesis of dihydropyranone and dihydropyridinone products bearing polyfluorinated stereocenters (29 examples...

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Detalles Bibliográficos
Autores principales:	Greenhalgh, Mark D., Qu, Shen, Slawin, Alexandra M. Z., Smith, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982221/ https://www.ncbi.nlm.nih.gov/pubmed/29910944 http://dx.doi.org/10.1039/c8sc01324a

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