Treatment with the PPARγ Agonist Pioglitazone in the Early Post-ischemia Phase Inhibits Pro-inflammatory Responses and Promotes Neurogenesis Via the Activation of Innate- and Bone Marrow-Derived Stem Cells in Rats

Neurogenesis is essential for a good post-stroke outcome. Exogenous stem cells are currently being tested to promote neurogenesis after stroke. Elsewhere, we demonstrated that treatment with the PPARγ agonist pioglitazone (PGZ) before cerebral ischemia induction reduced brain damage and activated su...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinouchi, Tomoya, Kitazato, Keiko T., Shimada, Kenji, Yagi, Kenji, Tada, Yoshiteru, Matsushita, Nobuhisa, Kurashiki, Yoshitaka, Satomi, Junichiro, Sata, Masataka, Nagahiro, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982463/
https://www.ncbi.nlm.nih.gov/pubmed/29110250
http://dx.doi.org/10.1007/s12975-017-0577-8

Ejemplares similares

Ejemplares similares