Efficacy and Safety of Fosmidomycin–Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon

BACKGROUND: Fosmidomycin–piperaquine is being developed as nonartemisinin-based combination therapy to meet the challenge of emerging artemisinin resistance. METHODS: The study was a phase 2, single-arm, proof-of-concept study of the efficacy, tolerability, and safety of fosmidomycin–piperaquine for...

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Detalles Bibliográficos
Autores principales: Mombo-Ngoma, Ghyslain, Remppis, Jonathan, Sievers, Moritz, Zoleko Manego, Rella, Endamne, Lilian, Kabwende, Lumeka, Veletzky, Luzia, Nguyen, The Trong, Groger, Mirjam, Lötsch, Felix, Mischlinger, Johannes, Flohr, Lena, Kim, Johanna, Cattaneo, Chiara, Hutchinson, David, Duparc, Stephan, Moehrle, Joerg, Velavan, Thirumalaisamy P, Lell, Bertrand, Ramharter, Michael, Adegnika, Ayola Akim, Mordmüller, Benjamin, Kremsner, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles and Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982710/
https://www.ncbi.nlm.nih.gov/pubmed/29293893
http://dx.doi.org/10.1093/cid/cix1122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982710/
https://www.ncbi.nlm.nih.gov/pubmed/29293893
http://dx.doi.org/10.1093/cid/cix1122

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