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High salt induces P-glycoprotein mediated treatment resistance in breast cancer cells through store operated calcium influx

Recent evidence from our laboratory has demonstrated that high salt (Δ0.05 M NaCl) induced inflammatory response and cancer cell proliferation through salt inducible kinase-3 (SIK3) upregulation. As calcium influx is known to effect inflammatory response and drug resistance, we examined the impact o...

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Detalles Bibliográficos
Autores principales: Babaer, Duaa, Amara, Suneetha, Ivy, Michael, Zhao, Yan, Lammers, Philip E., Titze, Jens M., Tiriveedhi, Venkataswarup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982760/
https://www.ncbi.nlm.nih.gov/pubmed/29861863
http://dx.doi.org/10.18632/oncotarget.25391