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Mutational spectrum of acute myeloid leukemia patients with double CEBPA mutations based on next-generation sequencing and its prognostic significance

The aim of this study was to profile the spectrum of genetic mutations in acute myeloid leukemia (AML) patients co-occurring with CEBPA double mutation (CEBPA(dm)). Between January 1, 2012, and June 30, 2017, 553 consecutive patients with de novo AML were screened for CEBPA mutations. Out of these,...

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Detalles Bibliográficos
Autores principales: Su, Long, Tan, YeHui, Lin, Hai, Liu, XiaoLiang, Yu, Li, Yang, YanPing, Liu, ShanShan, Bai, Ou, Yang, Yan, Jin, FengYan, Sun, JingNan, Liu, ChunShui, Liu, QiuJu, Gao, SuJun, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982761/
https://www.ncbi.nlm.nih.gov/pubmed/29861846
http://dx.doi.org/10.18632/oncotarget.23873