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The B cell receptor signaling pathway in mantle cell lymphoma

Signal transduction through the constitutively activated B cell receptor (BCR) plays a key role in the pathogenesis of B-cell tumors by promoting survival and proliferation of malignant B cells. The BCR signaling pathway is known to be deregulated in Mantle Cell Lymphoma (MCL) due to mutations or ep...

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Detalles Bibliográficos
Autores principales: Merolle, Maria I., Ahmed, Makhdum, Nomie, Krystle, Wang, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982769/
https://www.ncbi.nlm.nih.gov/pubmed/29861875
http://dx.doi.org/10.18632/oncotarget.25011