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Breast and ovarian cancer penetrance of BRCA1/2 mutations among Hong Kong women

Germline mutations in BRCA1 and BRCA2 (BRCA1/2) are associated with increased risk of breast and ovarian cancer. The penetrance of breast and ovarian cancer in BRCA1/2 mutation carriers has been well characterized in Caucasian but not in Asian. Two studies have investigated the breast cancer risk in...

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Detalles Bibliográficos
Autores principales: Zhang, LingJiao, Shin, Vivian Y., Chai, Xinglei, Zhang, Alan, Chan, Tsun L., Ma, Edmond S., Rebbeck, Timothy R., Chen, Jinbo, Kwong, Ava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982775/
https://www.ncbi.nlm.nih.gov/pubmed/29861850
http://dx.doi.org/10.18632/oncotarget.24382