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Spotlight on olaparib in the treatment of BRCA-mutated ovarian cancer: design, development and place in therapy

Epithelial ovarian cancer is the sixth most common cancer among women worldwide and the first cause of death among gynecological malignancies. Most of the patients present recurrent disease and unfortunately cannot be cured. The unsatisfactory results obtained with salvage chemotherapy have elicited...

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Detalles Bibliográficos
Autores principales: Lorusso, Domenica, Tripodi, Elisa, Maltese, Giuseppa, Lepori, Stefano, Sabatucci, Ilaria, Bogani, Giorgio, Raspagliesi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983012/
https://www.ncbi.nlm.nih.gov/pubmed/29881257
http://dx.doi.org/10.2147/DDDT.S124447