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Insulin receptor based lymphocyte trafficking in the progression of type 1 diabetes

The insulin receptor (IR) is a transmembrane receptor which recognizes and binds the hormone insulin. We describe two models that were devised to explore the role of IR over-expression on T-lymphocytes and their chemotactic motility in the progression of type 1 diabetes. FVB/NJ-CD3-3×FLAG-mIR/MFM mi...

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Detalles Bibliográficos
Autores principales:	Morran, Michael P., Al-Dieri, Ali G., Nestor-Kalinoski, Andrea L., Jordan, Richard K., Gupta, Nirdesh K., McInerney, Marcia F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of Biological Methods 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983036/ https://www.ncbi.nlm.nih.gov/pubmed/29862308 http://dx.doi.org/10.14440/jbm.2018.209

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