Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver damage and has a strong genetic component. The rs4841132 G>A variant, modulating the expression of protein phosphatase 1 regulatory subunit 3B (PPP1R3B), which is involved in glycogen synthesis, has been reported to reduce the ris...

Descripción completa

Detalles Bibliográficos
Autores principales: Dongiovanni, Paola, Meroni, Marica, Mancina, Rosellina M., Baselli, Guido, Rametta, Raffaela, Pelusi, Serena, Männistö, Ville, Fracanzani, Anna L., Badiali, Sara, Miele, Luca, Grimaudo, Stefania, Petta, Salvatore, Bugianesi, Elisabetta, Soardo, Giorgio, Fargion, Silvia, Pihlajamäki, Jussi, Romeo, Stefano, Valenti, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983109/
https://www.ncbi.nlm.nih.gov/pubmed/29881818
http://dx.doi.org/10.1002/hep4.1192

Ejemplares similares

Ejemplares similares