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NMDAR‐dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity
MicroRNAs (miRNAs) repress translation of target mRNAs by associating with Argonaute (Ago) proteins to form the RNA‐induced silencing complex (RISC), underpinning a powerful mechanism for fine‐tuning protein expression. Specific miRNAs are required for NMDA receptor (NMDAR)‐dependent synaptic plasti...
Autores principales: | Rajgor, Dipen, Sanderson, Thomas M, Amici, Mascia, Collingridge, Graham L, Hanley, Jonathan G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983126/ https://www.ncbi.nlm.nih.gov/pubmed/29712715 http://dx.doi.org/10.15252/embj.201797943 |
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