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NMDAR‐dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity

MicroRNAs (miRNAs) repress translation of target mRNAs by associating with Argonaute (Ago) proteins to form the RNA‐induced silencing complex (RISC), underpinning a powerful mechanism for fine‐tuning protein expression. Specific miRNAs are required for NMDA receptor (NMDAR)‐dependent synaptic plasti...

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Detalles Bibliográficos
Autores principales: Rajgor, Dipen, Sanderson, Thomas M, Amici, Mascia, Collingridge, Graham L, Hanley, Jonathan G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983126/
https://www.ncbi.nlm.nih.gov/pubmed/29712715
http://dx.doi.org/10.15252/embj.201797943

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