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DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34(+) CD15(−) cells in early chronic‐phase chronic myeloid leukemia

Despite the high efficiency of tyrosine kinase inhibitors (TKI), some patients with chronic myeloid leukemia (CML) will display residual disease that can become resistant to treatment, indicating intraclonal heterogeneity in chronic‐phase CML (CP‐CML). To determine the basis of this heterogeneity, w...

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Detalles Bibliográficos
Autores principales:	Maupetit‐Mehouas, Stéphanie, Court, Franck, Bourgne, Céline, Guerci‐Bresler, Agnès, Cony‐Makhoul, Pascale, Johnson, Hyacinthe, Etienne, Gabriel, Rousselot, Philippe, Guyotat, Denis, Janel, Alexandre, Hermet, Eric, Saugues, Sandrine, Berger, Juliette, Arnaud, Philippe, Berger, Marc G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983208/ https://www.ncbi.nlm.nih.gov/pubmed/29575763 http://dx.doi.org/10.1002/1878-0261.12191

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