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Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents

The absence of biomarkers to accurately predict anticancer therapy response remains a major obstacle in clinical oncology. We applied a genome‐wide loss‐of‐function screening approach in human haploid cells to characterize genetic vulnerabilities to classical microtubule‐targeting agents. Using doce...

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Detalles Bibliográficos
Autores principales:	Gerhards, Nora M., Blomen, Vincent A., Mutlu, Merve, Nieuwenhuis, Joppe, Howald, Denise, Guyader, Charlotte, Jonkers, Jos, Brummelkamp, Thijn R., Rottenberg, Sven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983209/ https://www.ncbi.nlm.nih.gov/pubmed/29689640 http://dx.doi.org/10.1002/1878-0261.12307

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