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Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins

Small molecule toxins such as mycotoxins with low molecular weight are the most widely studied biological toxins. These biological toxins are responsible for food poisoning and have the potential to be used as biological warfare agents at the toxic dose. Due to the poisonous nature of mycotoxins, ef...

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Detalles Bibliográficos
Autores principales: Sharma, Atul, Khan, Reem, Catanante, Gaelle, Sherazi, Tauqir A., Bhand, Sunil, Hayat, Akhtar, Marty, Jean Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983253/
https://www.ncbi.nlm.nih.gov/pubmed/29751687
http://dx.doi.org/10.3390/toxins10050197
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author Sharma, Atul
Khan, Reem
Catanante, Gaelle
Sherazi, Tauqir A.
Bhand, Sunil
Hayat, Akhtar
Marty, Jean Louis
author_facet Sharma, Atul
Khan, Reem
Catanante, Gaelle
Sherazi, Tauqir A.
Bhand, Sunil
Hayat, Akhtar
Marty, Jean Louis
author_sort Sharma, Atul
collection PubMed
description Small molecule toxins such as mycotoxins with low molecular weight are the most widely studied biological toxins. These biological toxins are responsible for food poisoning and have the potential to be used as biological warfare agents at the toxic dose. Due to the poisonous nature of mycotoxins, effective analysis techniques for quantifying their toxicity are indispensable. In this context, biosensors have been emerged as a powerful tool to monitors toxins at extremely low level. Recently, biosensors based on fluorescence detection have attained special interest with the incorporation of nanomaterials. This review paper will focus on the development of fluorescence-based biosensors for mycotoxin detection, with particular emphasis on their design as well as properties such as sensitivity and specificity. A number of these fluorescent biosensors have shown promising results in food samples for the detection of mycotoxins, suggesting their future potential for food applications.
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spelling pubmed-59832532018-06-06 Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins Sharma, Atul Khan, Reem Catanante, Gaelle Sherazi, Tauqir A. Bhand, Sunil Hayat, Akhtar Marty, Jean Louis Toxins (Basel) Review Small molecule toxins such as mycotoxins with low molecular weight are the most widely studied biological toxins. These biological toxins are responsible for food poisoning and have the potential to be used as biological warfare agents at the toxic dose. Due to the poisonous nature of mycotoxins, effective analysis techniques for quantifying their toxicity are indispensable. In this context, biosensors have been emerged as a powerful tool to monitors toxins at extremely low level. Recently, biosensors based on fluorescence detection have attained special interest with the incorporation of nanomaterials. This review paper will focus on the development of fluorescence-based biosensors for mycotoxin detection, with particular emphasis on their design as well as properties such as sensitivity and specificity. A number of these fluorescent biosensors have shown promising results in food samples for the detection of mycotoxins, suggesting their future potential for food applications. MDPI 2018-05-11 /pmc/articles/PMC5983253/ /pubmed/29751687 http://dx.doi.org/10.3390/toxins10050197 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sharma, Atul
Khan, Reem
Catanante, Gaelle
Sherazi, Tauqir A.
Bhand, Sunil
Hayat, Akhtar
Marty, Jean Louis
Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins
title Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins
title_full Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins
title_fullStr Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins
title_full_unstemmed Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins
title_short Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins
title_sort designed strategies for fluorescence-based biosensors for the detection of mycotoxins
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983253/
https://www.ncbi.nlm.nih.gov/pubmed/29751687
http://dx.doi.org/10.3390/toxins10050197
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