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Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)

Prior research has established the Gait Variability Index (GVI) as a composite measure of gait variability, based on spatiotemporal parameters, that is associated with functional outcomes. However, under certain circumstances the magnitude and directional specificity of the GVI is adversely affected...

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Autores principales: Gouelle, Arnaud, Rennie, Linda, Clark, David J., Mégrot, Fabrice, Balasubramanian, Chitralakshmi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983480/
https://www.ncbi.nlm.nih.gov/pubmed/29856818
http://dx.doi.org/10.1371/journal.pone.0198267
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author Gouelle, Arnaud
Rennie, Linda
Clark, David J.
Mégrot, Fabrice
Balasubramanian, Chitralakshmi K.
author_facet Gouelle, Arnaud
Rennie, Linda
Clark, David J.
Mégrot, Fabrice
Balasubramanian, Chitralakshmi K.
author_sort Gouelle, Arnaud
collection PubMed
description Prior research has established the Gait Variability Index (GVI) as a composite measure of gait variability, based on spatiotemporal parameters, that is associated with functional outcomes. However, under certain circumstances the magnitude and directional specificity of the GVI is adversely affected by shortcomings in the calculation method. Here we present an enhanced gait variability index (EGVI) that addresses those shortcomings and improves the utility of the measure. The EGVI was further enhanced by removing some input spatiotemporal variables that captured overlapping/redundant information. The EGVI was used to reanalyze data from four previously published studies that used the original GVI. After removing data affected by the GVI’s prior shortcomings, the association between EGVI and GVI values was stronger for the pooled dataset (r(2) = 0.95) and for the individual studies (r(2) = 0.88–0.98). The EGVI also revealed stronger associations between the index value and functional outcomes for some studies. The EGVI successfully addresses shortcomings in the GVI calculation that affected magnitude and directional specificity of the index. We have confirmed the validity of prior published work that used the original GVI, while also demonstrating even stronger results when these prior data were re-analyzed with the EGVI. We recommend that future research should use the EGVI as a composite measure of gait variability.
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spelling pubmed-59834802018-06-17 Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI) Gouelle, Arnaud Rennie, Linda Clark, David J. Mégrot, Fabrice Balasubramanian, Chitralakshmi K. PLoS One Research Article Prior research has established the Gait Variability Index (GVI) as a composite measure of gait variability, based on spatiotemporal parameters, that is associated with functional outcomes. However, under certain circumstances the magnitude and directional specificity of the GVI is adversely affected by shortcomings in the calculation method. Here we present an enhanced gait variability index (EGVI) that addresses those shortcomings and improves the utility of the measure. The EGVI was further enhanced by removing some input spatiotemporal variables that captured overlapping/redundant information. The EGVI was used to reanalyze data from four previously published studies that used the original GVI. After removing data affected by the GVI’s prior shortcomings, the association between EGVI and GVI values was stronger for the pooled dataset (r(2) = 0.95) and for the individual studies (r(2) = 0.88–0.98). The EGVI also revealed stronger associations between the index value and functional outcomes for some studies. The EGVI successfully addresses shortcomings in the GVI calculation that affected magnitude and directional specificity of the index. We have confirmed the validity of prior published work that used the original GVI, while also demonstrating even stronger results when these prior data were re-analyzed with the EGVI. We recommend that future research should use the EGVI as a composite measure of gait variability. Public Library of Science 2018-06-01 /pmc/articles/PMC5983480/ /pubmed/29856818 http://dx.doi.org/10.1371/journal.pone.0198267 Text en © 2018 Gouelle et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Gouelle, Arnaud
Rennie, Linda
Clark, David J.
Mégrot, Fabrice
Balasubramanian, Chitralakshmi K.
Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)
title Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)
title_full Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)
title_fullStr Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)
title_full_unstemmed Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)
title_short Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI)
title_sort addressing limitations of the gait variability index to enhance its applicability: the enhanced gvi (egvi)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983480/
https://www.ncbi.nlm.nih.gov/pubmed/29856818
http://dx.doi.org/10.1371/journal.pone.0198267
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