Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice

BACKGROUND: Polymeric immunoglobulin receptor (pIgR) transport of secretory immunoglobulin A (SIgA) to mucosal surfaces is thought to promote gut integrity and immunity to Salmonella enterica serovar Typhimurium (S. Typhimurium), an invasive pathogen in mice. To elucidate potential mechanisms, we as...

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Detalles Bibliográficos
Autores principales: Betz, Kristina J., Maier, Elizabeth A., Amarachintha, Surya, Wu, David, Karmele, Erik P., Kinder, Jeremy M., Steinbrecher, Kris A., McNeal, Monica M., Luzader, Deborah H., Hogan, Simon P., Moore, Sean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983570/
https://www.ncbi.nlm.nih.gov/pubmed/29856838
http://dx.doi.org/10.1371/journal.pone.0198434

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