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Glucosamine-Induced Autophagy through AMPK–mTOR Pathway Attenuates Lipofuscin-Like Autofluorescence in Human Retinal Pigment Epithelial Cells In Vitro

Age-related macular degeneration (AMD) is a vision-threatening age-associated disease. The retinal pigment epithelial (RPE) cells phagocytose and digest photoreceptor outer segment (POS). Incomplete digestion of POS leads to lipofuscin accumulation, which contributes to the pathology of the AMD. Aut...

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Detalles Bibliográficos
Autores principales:	Chen, Ching-Long, Chen, Yi-Hao, Liang, Chang-Min, Tai, Ming-Cheng, Lu, Da-Wen, Chen, Jiann-Torng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983587/ https://www.ncbi.nlm.nih.gov/pubmed/29747425 http://dx.doi.org/10.3390/ijms19051416

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