Cargando…

Frizzled Receptors as Potential Therapeutic Targets in Human Cancers

Frizzled receptors (FZDs) are a family of seven-span transmembrane receptors with hallmarks of G protein-coupled receptors (GPCRs) that serve as receptors for secreted Wingless-type (WNT) ligands in the WNT signaling pathway. Functionally, FZDs play crucial roles in regulating cell polarity, embryon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Chui-Mian, Chen, Zhe, Fu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983605/ https://www.ncbi.nlm.nih.gov/pubmed/29789460 http://dx.doi.org/10.3390/ijms19051543

Ejemplares similares

Cancer chemoprevention through Frizzled receptors and EMT
por: Sompel, K., et al.
Publicado: (2021)

Deregulation of Frizzled Receptors in Hepatocellular Carcinoma
por: Chan, Kristy Kwan-Shuen, et al.
Publicado: (2018)

Frizzled7: A Promising Achilles’ Heel for Targeting the Wnt Receptor Complex to Treat Cancer
por: Phesse, Toby, et al.
Publicado: (2016)

Frizzled Receptors in Tumors, Focusing on Signaling, Roles, Modulation Mechanisms, and Targeted Therapies
por: Sun, Yu, et al.
Publicado: (2021)

MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8
por: Xu, Lingling, et al.
Publicado: (2016)

Fatty acid recognition in the Frizzled receptor family
por: Nile, Aaron H., et al.
Publicado: (2019)

Non-Coding RNA and Frizzled Receptors in Cancer
por: Smith, Alex J., et al.
Publicado: (2021)

Signaling of Human Frizzled Receptors to the Mating Pathway in Yeast
por: Dirnberger, Dietmar, et al.
Publicado: (2007)

Frizzled receptors in melanomagenesis: From molecular interactions to target identification
por: Umar, Sheikh A., et al.
Publicado: (2022)

Discovery of novel frizzled-7 inhibitors by targeting the receptor’s transmembrane domain
por: Zhang, Wei, et al.
Publicado: (2017)

Frizzled-2: A potential novel target for molecular pancreatic cancer therapy
por: TOMIZAWA, MINORU, et al.
Publicado: (2014)

The Frizzled family: receptors for multiple signal transduction pathways
por: Huang, Hui-Chuan, et al.
Publicado: (2004)

Identification of therapeutic targets and prognostic biomarkers among frizzled family genes in glioma
por: Huang, Ke, et al.
Publicado: (2023)

The Levels of Wnt5a and Its Receptors Frizzled5 and Frizzled2 as Immunohistochemical Biomarkers of Severity of Psoriasis
por: Ning, Xiaoying, et al.
Publicado: (2021)

Iloprost requires the Frizzled-9 receptor to prevent lung cancer
por: Sompel, Kayla, et al.
Publicado: (2022)

Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma
por: Bengochea, A, et al.
Publicado: (2008)

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families
por: Voloshanenko, Oksana, et al.
Publicado: (2017)

Control of bone formation by the serpentine receptor Frizzled-9
por: Albers, Joachim, et al.
Publicado: (2011)

Frizzled-1 receptor regulates adult hippocampal neurogenesis
por: Mardones, Muriel D., et al.
Publicado: (2016)

The G protein-coupled receptor identity of the frizzled proteins
por: Katanaev, VL, et al.
Publicado: (2009)

Expression of the Wnt Receptor Frizzled-4 in the Human Enteric Nervous System of Infants
por: Nothelfer, Katharina, et al.
Publicado: (2016)

Role of Frizzled receptor expression on patients’ survival with gastrointestinal cancers: A systematic review with meta-analysis
por: Hafezi, Nasim, et al.
Publicado: (2022)

Targeting fatty acid synthase sensitizes human nasopharyngeal carcinoma cells to radiation via downregulating frizzled class receptor 10
por: Chen, Jiongyu, et al.
Publicado: (2020)

Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function
por: Varela-Nallar, Lorena, et al.
Publicado: (2009)

Frizzled are colonic epithelial receptors for Clostridium difficile toxin B
por: Tao, Liang, et al.
Publicado: (2016)

Semaphorins or Frizzled –it is the receptor that direct the action of clostridial glucosylating toxins
por: Aktories, Klaus
Publicado: (2020)

Structure of the C-terminal Region of the Frizzled Receptor 1 in Detergent Micelles
por: Gayen, Shovanlal, et al.
Publicado: (2013)

Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children
por: Neckel, Peter H., et al.
Publicado: (2019)

Nuclear Receptors as Potential Therapeutic Targets for Myeloid Leukemia
por: Pan, Pan, et al.
Publicado: (2020)

Frizzled-5 Receptor Is Involved in Neuronal Polarity and Morphogenesis of Hippocampal Neurons
por: Slater, Paula G., et al.
Publicado: (2013)

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells
por: Avilés, Evelyn C., et al.
Publicado: (2014)

USP10 as a Potential Therapeutic Target in Human Cancers
por: Tao, Li, et al.
Publicado: (2022)

Human Cancer and Platelet Interaction, a Potential Therapeutic Target
por: Wang, Shike, et al.
Publicado: (2018)

Inhibition of Wnt/β-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8
por: Hendaoui, Ismaïl, et al.
Publicado: (2012)

Adenosine Receptors as Potential Therapeutic Analgesic Targets
por: Haddad, Mansour, et al.
Publicado: (2023)

Analysis of the role of Frizzled 2 in different cancer types
por: Zhou, Miaomiao, et al.
Publicado: (2021)

Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1
por: Yu, Shibing, et al.
Publicado: (2016)

Therapeutic Potential of Targeting Prokineticin Receptors in Diseases
por: Vincenzi, Martina, et al.
Publicado: (2023)

Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer
por: Bravo, Dawn T, et al.
Publicado: (2013)

Correction: Inhibition of Wnt/β-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8
por: Hendaoui, Ismaïl, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_8tbesos26a2jtc83opktm10u40