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Frizzled Receptors as Potential Therapeutic Targets in Human Cancers

Frizzled receptors (FZDs) are a family of seven-span transmembrane receptors with hallmarks of G protein-coupled receptors (GPCRs) that serve as receptors for secreted Wingless-type (WNT) ligands in the WNT signaling pathway. Functionally, FZDs play crucial roles in regulating cell polarity, embryon...

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Detalles Bibliográficos
Autores principales:	Zeng, Chui-Mian, Chen, Zhe, Fu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983605/ https://www.ncbi.nlm.nih.gov/pubmed/29789460 http://dx.doi.org/10.3390/ijms19051543

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