Cargando…

Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer

Iron is an essential element for the growth and proliferation of cells. Cellular iron uptake, storage, utilization and export are tightly regulated to maintain iron homeostasis. However, cellular iron metabolism pathways are disturbed in most cancer cells. To maintain rapid growth and proliferation,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Liangfu, Zhao, Bin, Zhang, Lixiu, Wang, Shenghang, Dong, Dandan, Lv, Huanhuan, Shang, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983609/ https://www.ncbi.nlm.nih.gov/pubmed/29789480 http://dx.doi.org/10.3390/ijms19051545

Ejemplares similares

Iron Chelator Induces Apoptosis in Osteosarcoma Cells by Disrupting Intracellular Iron Homeostasis and Activating the MAPK Pathway
por: Xue, Yanru, et al.
Publicado: (2021)

Iron and leukemia: new insights for future treatments
por: Wang, Fang, et al.
Publicado: (2019)

β-Phenethyl Isothiocyanate Induces Cell Death in Human Osteosarcoma through Altering Iron Metabolism, Disturbing the Redox Balance, and Activating the MAPK Signaling Pathway
por: Lv, Huanhuan, et al.
Publicado: (2020)

Moderate static magnetic field promotes fracture healing and regulates iron metabolism in mice
por: Wang, Shenghang, et al.
Publicado: (2023)

Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities
por: De Matteis, Serena, et al.
Publicado: (2018)

Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
por: Zhang, Bin, et al.
Publicado: (2023)

Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities
por: Miao, Runyu, et al.
Publicado: (2023)

Regulation of cellular iron metabolism
por: Wang, Jian, et al.
Publicado: (2011)

Alteration of cellular metabolism in cancer cells and its therapeutic prospects
por: Biswal, Biranchi Narayan, et al.
Publicado: (2017)

Metabolic alterations due to IDH1 mutation in glioma: opening for therapeutic opportunities?
por: N Mustafa, Dana A, et al.
Publicado: (2014)

Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
por: Zhang, Caiguo, et al.
Publicado: (2014)

Cellular iron homeostasis and metabolism in plant
por: Vigani, Gianpiero, et al.
Publicado: (2013)

On the Quest of Cellular Functions of PEA-15 and the Therapeutic Opportunities
por: Wei, Yufeng
Publicado: (2015)

Editorial: Cellular Senescence: Causes, Consequences and Therapeutic Opportunities
por: Wong, Pooi-Fong
Publicado: (2022)

Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
por: Li, Yin, et al.
Publicado: (2021)

Co-located Retail Clinics and Pharmacies: An Opportunity to Provide More Primary Care
por: Knapp, Katherine, et al.
Publicado: (2019)

Alginate-Iron Speciation and Its Effect on In Vitro Cellular Iron Metabolism
por: Horniblow, Richard D., et al.
Publicado: (2015)

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
por: Palmer, Allyson K., et al.
Publicado: (2015)

Isocitrate dehydrogenase variants in cancer — Cellular consequences and therapeutic opportunities
por: Liu, Shuang, et al.
Publicado: (2020)

Editorial: Cellular stress in blood cancer: Pathophysiology and therapeutic opportunities
por: Costoya, José A., et al.
Publicado: (2022)

Stem Cell Transplantation for Peripheral Nerve Regeneration: Current Options and Opportunities
por: Jiang, Liangfu, et al.
Publicado: (2017)

Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities
por: Prola, Alexandre, et al.
Publicado: (2022)

In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution
por: Gasperini, Lisa, et al.
Publicado: (2016)

Iron Metabolism in Cancer and Senescence: A Cellular Perspective
por: Crescenzi, Elvira, et al.
Publicado: (2023)

CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism
por: Han, Yingying, et al.
Publicado: (2023)

Editorial: Tumor adaptation to cellular stresses: mechanisms, biomarkers and therapeutic opportunities
por: Cortesi, Michela, et al.
Publicado: (2023)

Higher iron pearl millet (Pennisetum glaucum L.) provides more absorbable iron that is limited by increased polyphenolic content
por: Tako, Elad, et al.
Publicado: (2015)

The MYB transcription factor RcMYB1 plays a central role in rose anthocyanin biosynthesis
por: He, Guoren, et al.
Publicado: (2023)

Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities
por: Neitzel, Carina, et al.
Publicado: (2020)

The interaction between cellular senescence and chronic kidney disease as a therapeutic opportunity
por: Zhao, Jing-Li, et al.
Publicado: (2022)

Alterations in the Gut Microbiome and Metabolisms in Pregnancies with Fetal Growth Restriction
por: Tao, Zixin, et al.
Publicado: (2023)

Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges
por: Lei, Xiaotian, et al.
Publicado: (2022)

Mononuclear cell dynamics in M. tuberculosis infection provide opportunities for therapeutic intervention
por: Norris, Brian A., et al.
Publicado: (2018)

Metabolic alterations in cancer cells and therapeutic implications
por: Hammoudi, Naima, et al.
Publicado: (2011)

Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation
por: Martelli, Alain, et al.
Publicado: (2014)

Regorafenib Alteration of the BCL-xL/MCL-1 Ratio Provides a Therapeutic Opportunity for BH3-Mimetics in Hepatocellular Carcinoma Models
por: Cucarull, Blanca, et al.
Publicado: (2020)

SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1
por: Jeong, Seung Min, et al.
Publicado: (2014)

Ultrasound and Nanomedicine for Cancer-Targeted Drug Delivery: Screening, Cellular Mechanisms and Therapeutic Opportunities
por: Li, Chien-Hsiu, et al.
Publicado: (2022)

Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities
por: Silwal, Prashanta, et al.
Publicado: (2023)

Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities
por: Blijlevens, Maxime, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jnt08qpdt3jddi9j51uvijumcl