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Growth Hormone Receptor Mutations Related to Individual Dwarfism

Growth hormone (GH) promotes body growth by binding with two GH receptors (GHRs) at the cell surface. GHRs interact with Janus kinase, signal transducers, and transcription activators to stimulate metabolic effects and insulin-like growth factor (IGF) synthesis. However, process dysfunctions in the...

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Detalles Bibliográficos
Autores principales: Lin, Shudai, Li, Congjun, Li, Charles, Zhang, Xiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983672/
https://www.ncbi.nlm.nih.gov/pubmed/29748515
http://dx.doi.org/10.3390/ijms19051433