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Integrative Bioinformatics and Functional Analyses of GEO, ENCODE, and TCGA Reveal FADD as a Direct Target of the Tumor Suppressor BRCA1

BRCA1 is a multifunctional tumor suppressor involved in several essential cellular processes. Although many of these functions are driven by or related to its transcriptional/epigenetic regulator activity, there has been no genome-wide study to reveal the transcriptional/epigenetic targets of BRCA1....

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Detalles Bibliográficos
Autores principales: Nguyen, Dinh-Duc, Lee, Dong Gyu, Kim, Sinae, Kang, Keunsoo, Rhee, Je-keun, Chang, Suhwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983697/
https://www.ncbi.nlm.nih.gov/pubmed/29757984
http://dx.doi.org/10.3390/ijms19051458