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The Interaction of the Metallo-Glycopeptide Anti-Tumour Drug Bleomycin with DNA
The cancer chemotherapeutic drug, bleomycin, is clinically used to treat several neoplasms including testicular and ovarian cancers. Bleomycin is a metallo-glycopeptide antibiotic that requires a transition metal ion, usually Fe(II), for activity. In this review, the properties of bleomycin are exam...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983701/ https://www.ncbi.nlm.nih.gov/pubmed/29734689 http://dx.doi.org/10.3390/ijms19051372 |