SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease

In 1993, Rosen and collaborators discovered that the gene encoding SOD1 has mutations in amyotrophic lateral sclerosis (ALS) patients; moreover, these mutations are found in the exon regions, suggesting that their toxic effects are the consequence of protein dysfunction with an increase of oxidative...

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Detalles Bibliográficos
Autores principales: Pansarasa, Orietta, Bordoni, Matteo, Diamanti, Luca, Sproviero, Daisy, Gagliardi, Stella, Cereda, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983710/
https://www.ncbi.nlm.nih.gov/pubmed/29751510
http://dx.doi.org/10.3390/ijms19051345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983710/
https://www.ncbi.nlm.nih.gov/pubmed/29751510
http://dx.doi.org/10.3390/ijms19051345

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