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mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression

The mammalian target of rapamycin (mTOR) pathway is overactivated in thyroid cancer (TC). We previously demonstrated that phospho-mTOR expression is associated with tumor aggressiveness, therapy resistance, and lower mRNA expression of SLC5A5 in papillary thyroid carcinoma (PTC), while phospho-S6 (m...

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Detalles Bibliográficos
Autores principales:	Tavares, Catarina, Eloy, Catarina, Melo, Miguel, Gaspar da Rocha, Adriana, Pestana, Ana, Batista, Rui, Bueno Ferreira, Luciana, Rios, Elisabete, Sobrinho Simões, Manuel, Soares, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983778/ https://www.ncbi.nlm.nih.gov/pubmed/29757257 http://dx.doi.org/10.3390/ijms19051448

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