PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism

PIMT/NCOA6IP, a transcriptional coactivator PRIP/NCOA6 binding protein, enhances nuclear receptor transcriptional activity. Germline disruption of PIMT results in early embryonic lethality due to impairment of development around blastocyst and uterine implantation stages. We now generated mice with...

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Detalles Bibliográficos
Autores principales: Jia, Yuzhi, Liu, Ning, Viswakarma, Navin, Sun, Ruya, Schipma, Mathew J., Shang, Meng, Thorp, Edward B., Kanwar, Yashpal S., Thimmapaya, Bayar, Reddy, Janardan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983783/
https://www.ncbi.nlm.nih.gov/pubmed/29772707
http://dx.doi.org/10.3390/ijms19051485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983783/
https://www.ncbi.nlm.nih.gov/pubmed/29772707
http://dx.doi.org/10.3390/ijms19051485

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