Cargando…

PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism

PIMT/NCOA6IP, a transcriptional coactivator PRIP/NCOA6 binding protein, enhances nuclear receptor transcriptional activity. Germline disruption of PIMT results in early embryonic lethality due to impairment of development around blastocyst and uterine implantation stages. We now generated mice with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Yuzhi, Liu, Ning, Viswakarma, Navin, Sun, Ruya, Schipma, Mathew J., Shang, Meng, Thorp, Edward B., Kanwar, Yashpal S., Thimmapaya, Bayar, Reddy, Janardan K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983783/ https://www.ncbi.nlm.nih.gov/pubmed/29772707 http://dx.doi.org/10.3390/ijms19051485

Ejemplares similares

ERK2-Mediated Phosphorylation of Transcriptional Coactivator Binding Protein PIMT/NCoA6IP at Ser(298) Augments Hepatic Gluconeogenesis
por: Kapadia, Bandish, et al.
Publicado: (2013)

Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
por: Jia, Yuzhi, et al.
Publicado: (2016)

Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
por: Jia, Yuzhi, et al.
Publicado: (2016)

Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα
por: Shete, Varsha, et al.
Publicado: (2018)

Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4
por: Kain, Vasundhara, et al.
Publicado: (2015)

PIMT regulates hepatic gluconeogenesis in mice
por: Kapadia, Bandish, et al.
Publicado: (2023)

Coactivators in PPAR-Regulated Gene Expression
por: Viswakarma, Navin, et al.
Publicado: (2010)

PIMT is a novel and potent suppressor of endothelial activation
por: Zhang, Chen, et al.
Publicado: (2023)

PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex
por: Pyper, Sean R., et al.
Publicado: (2010)

PIMT Controls Insulin Synthesis and Secretion through PDX1
por: Sharma, Rahul, et al.
Publicado: (2023)

PPARα: energy combustion, hypolipidemia, inflammation and cancer
por: Pyper, Sean R., et al.
Publicado: (2010)

Effect of gold nanoparticles on the structure and neuroprotective function of protein L-isoaspartyl methyltransferase (PIMT)
por: Chatterjee, Tanaya, et al.
Publicado: (2021)

Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors
por: Sharma, Isha, et al.
Publicado: (2020)

FAK deletion accelerates liver regeneration after two-thirds partial hepatectomy
por: Shang, Na, et al.
Publicado: (2016)

Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse
por: Matsumoto, Kojiro, et al.
Publicado: (2010)

Protein-L-Isoaspartyl Methyltransferase (PIMT) Is Required for Survival of Salmonella Typhimurium at 42°C and Contributes to the Virulence in Poultry
por: Pesingi, Pavan K., et al.
Publicado: (2017)

PIMT Binding to C-Terminal Ala459 of CAIX Is Involved in Inside-Out Signaling Necessary for Its Catalytic Activity
por: Simko, Veronika, et al.
Publicado: (2020)

The Role of NCOA4-Mediated Ferritinophagy in Health and Disease
por: Santana-Codina, Naiara, et al.
Publicado: (2018)

Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain
por: Sun, Zheng, et al.
Publicado: (2020)

Crystal structure of the TLDc domain of human NCOA7-AS
por: Arnaud-Arnould, Mary, et al.
Publicado: (2021)

NCOA4: More than a receptor for ferritinophagy
por: Wang, Zheng, et al.
Publicado: (2022)

PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis
por: Vicente, Cláudia M, et al.
Publicado: (2009)

PIMT Prevents the Apoptosis of Endothelial Cells in Response to Glycated Low Density Lipoproteins and Protective Effects of Grape Seed Procyanidin B2
por: Li, Xiao-li, et al.
Publicado: (2013)

Essential roles for the nuclear receptor coactivator Ncoa3 in pluripotency
por: Percharde, Michelle, et al.
Publicado: (2013)

Association of NCOA3 polymorphisms with Dyslipidemia in the Chinese Han population
por: Yu, Mingxi, et al.
Publicado: (2015)

NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration
por: Quiles del Rey, Maria, et al.
Publicado: (2019)

Expression and clinical significance of NCOA5 in epithelial ovarian cancer
por: Song, Xiaoping, et al.
Publicado: (2023)

Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse
por: Dimitrijevic, Aleksandra, et al.
Publicado: (2014)

Correction: Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse
Publicado: (2014)

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
por: Mancias, Joseph D., et al.
Publicado: (2014)

Association of NCOA3 (AIB1) polymorphisms with breast cancer risk
por: Burwinkel, B, et al.
Publicado: (2005)

Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer
por: Yu, J, et al.
Publicado: (2016)

High affinity between CREBBP/p300 and NCOA evolved in vertebrates
por: Karlsson, Elin, et al.
Publicado: (2020)

NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice
por: Nai, Antonella, et al.
Publicado: (2020)

NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
por: Ohshima, Tomoko, et al.
Publicado: (2022)

VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
por: Watson, Sarah, et al.
Publicado: (2023)

Oxygen modulates iron homeostasis by switching iron sensing of NCOA4
por: Kuno, Sota, et al.
Publicado: (2023)

p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis
por: Ghosh, Asish K, et al.
Publicado: (2013)

Transcription Factors in Cancer Development and Therapy
por: Vishnoi, Kanchan, et al.
Publicado: (2020)

Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6
por: Russo, Luigi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bqnpmmtiier2qjt7ad839nur4u