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Knockout of Pannexin-1 Induces Hearing Loss

Mutations of gap junction connexin genes induce a high incidence of nonsyndromic hearing loss. Pannexin genes also encode gap junctional proteins in vertebrates. Recent studies demonstrated that Pannexin-1 (Panx1) deficiency in mice and mutation in humans are also associated with hearing loss. So fa...

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Detalles Bibliográficos
Autores principales: Chen, Jin, Liang, Chun, Zong, Liang, Zhu, Yan, Zhao, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983795/
https://www.ncbi.nlm.nih.gov/pubmed/29710868
http://dx.doi.org/10.3390/ijms19051332