Cargando…
Knockout of Pannexin-1 Induces Hearing Loss
Mutations of gap junction connexin genes induce a high incidence of nonsyndromic hearing loss. Pannexin genes also encode gap junctional proteins in vertebrates. Recent studies demonstrated that Pannexin-1 (Panx1) deficiency in mice and mutation in humans are also associated with hearing loss. So fa...
Autores principales: | Chen, Jin, Liang, Chun, Zong, Liang, Zhu, Yan, Zhao, Hong-Bo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983795/ https://www.ncbi.nlm.nih.gov/pubmed/29710868 http://dx.doi.org/10.3390/ijms19051332 |
Ejemplares similares
-
Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing
por: Chen, Jin, et al.
Publicado: (2015) -
Correction: Corrigendum: Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing
por: Chen, Jin, et al.
Publicado: (2017) -
Expression and function of pannexins in the inner ear and hearing
por: Zhao, Hong-Bo
Publicado: (2016) -
Endothelial function is impaired in conduit arteries of pannexin1 knockout mice
por: Gaynullina, Dina, et al.
Publicado: (2014) -
Pannexin1 knockout and blockade reduces ischemic stroke injury in female, but not in male mice
por: Freitas-Andrade, Moises, et al.
Publicado: (2017)