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Organ-Specific MicroRNAs (MIR122, 137, and 206) Contribute to Tissue Characteristics and Carcinogenesis by Regulating Pyruvate Kinase M1/2 (PKM) Expression

Pyruvate kinase is known as the glycolytic enzyme catalyzing the final step in glycolysis. In mammals, two different forms of it exist, i.e., pyruvate kinase M1/2 (PKM) and pyruvate kinase L/R (PKLR). Also, PKM has two isoforms, i.e., PKM1 and PKM2. These genes have tissue-specific distribution. Nam...

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Detalles Bibliográficos
Autores principales:	Taniguchi, Kohei, Sugito, Nobuhiko, Shinohara, Haruka, Kuranaga, Yuki, Inomata, Yosuke, Komura, Kazumasa, Uchiyama, Kazuhisa, Akao, Yukihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983799/ https://www.ncbi.nlm.nih.gov/pubmed/29695138 http://dx.doi.org/10.3390/ijms19051276

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