Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?

Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H...

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Detalles Bibliográficos
Autores principales: Li, Jackie, Perez Perez, Guillermo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983810/
https://www.ncbi.nlm.nih.gov/pubmed/29751550
http://dx.doi.org/10.3390/ijms19051353
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author Li, Jackie
Perez Perez, Guillermo I.
author_facet Li, Jackie
Perez Perez, Guillermo I.
author_sort Li, Jackie
collection PubMed
description Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H. pylori bacteria have been identified. It is possible that non-H. pylori may have a significant role in the development of gastric cancer. Here, we discuss the specific role of H. pylori as a potential trigger for events that may be conducive to gastric cancer, and consider whether or not the rest of the gastric microbiota represent an additional risk in the development of this disease.
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spelling pubmed-59838102018-06-05 Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer? Li, Jackie Perez Perez, Guillermo I. Int J Mol Sci Review Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H. pylori bacteria have been identified. It is possible that non-H. pylori may have a significant role in the development of gastric cancer. Here, we discuss the specific role of H. pylori as a potential trigger for events that may be conducive to gastric cancer, and consider whether or not the rest of the gastric microbiota represent an additional risk in the development of this disease. MDPI 2018-05-03 /pmc/articles/PMC5983810/ /pubmed/29751550 http://dx.doi.org/10.3390/ijms19051353 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li, Jackie
Perez Perez, Guillermo I.
Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?
title Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?
title_full Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?
title_fullStr Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?
title_full_unstemmed Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?
title_short Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?
title_sort is there a role for the non-helicobacter pylori bacteria in the risk of developing gastric cancer?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983810/
https://www.ncbi.nlm.nih.gov/pubmed/29751550
http://dx.doi.org/10.3390/ijms19051353
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