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Acetylation Disfavors Tau Phase Separation

Neuropathological aggregates of the intrinsically disordered microtubule-associated protein Tau are hallmarks of Alzheimer’s disease, with decades of research devoted to studying the protein’s aggregation properties both in vitro and in vivo. Recent demonstrations that Tau is capable of undergoing l...

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Detalles Bibliográficos
Autores principales: Ferreon, Josephine C., Jain, Antrix, Choi, Kyoung-Jae, Tsoi, Phoebe S., MacKenzie, Kevin R., Jung, Sung Yun, Ferreon, Allan Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983838/
https://www.ncbi.nlm.nih.gov/pubmed/29734651
http://dx.doi.org/10.3390/ijms19051360