Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

The lactose operon repressor protein LacI has long served as a paradigm of the bacterial transcription factors. However, the mechanisms whereby LacI rapidly locates its cognate binding site on the bacterial chromosome are still elusive. Single-molecule fluorescence imaging approaches are well suited...

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Detalles Bibliográficos
Autores principales: Kipper, Kalle, Eremina, Nadja, Marklund, Emil, Tubasum, Sumera, Mao, Guanzhong, Lehmann, Laura Christina, Elf, Johan, Deindl, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983854/
https://www.ncbi.nlm.nih.gov/pubmed/29856839
http://dx.doi.org/10.1371/journal.pone.0198416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983854/
https://www.ncbi.nlm.nih.gov/pubmed/29856839
http://dx.doi.org/10.1371/journal.pone.0198416

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