Cargando…

TGFβ signaling limits lineage plasticity in prostate cancer

Although treatment options for localized prostate cancer (CaP) are initially effective, the five-year survival for metastatic CaP is below 30%. Mutation or deletion of the PTEN tumor suppressor is a frequent event in metastatic CaP, and inactivation of the transforming growth factor (TGF) ß signalin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Yi, Bjerke, Glen A., Pietrzak, Karolina, Melhuish, Tiffany A., Han, Yu, Turner, Stephen D., Frierson, Henry F., Wotton, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983872/ https://www.ncbi.nlm.nih.gov/pubmed/29782499 http://dx.doi.org/10.1371/journal.pgen.1007409

Ejemplares similares

Prostate Cancer Induced by Loss of Apc Is Restrained by TGFβ Signaling
por: Bjerke, Glen A., et al.
Publicado: (2014)

Activation of Akt Signaling in Prostate Induces a TGFβ Mediated Restraint on Cancer Progression and Metastasis
por: Bjerke, Glen A., et al.
Publicado: (2013)

Premature Senescence and Increased TGFβ Signaling in the Absence of Tgif1
por: Zerlanko, Brad J., et al.
Publicado: (2012)

TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth
por: Shah, Anant, et al.
Publicado: (2019)

Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling
por: Kamata, Teddy, et al.
Publicado: (2021)

The Tgif2 gene contains a retained intron within the coding sequence
por: Melhuish, Tiffany A, et al.
Publicado: (2006)

plasticity of TGF-β signaling
por: Cellière, Geraldine, et al.
Publicado: (2011)

Tgif1 and Tgif2 Regulate Axial Patterning in Mouse
por: Melhuish, Tiffany A., et al.
Publicado: (2016)

Regulation of endothelial cell plasticity by TGF-β
por: van Meeteren, Laurens A., et al.
Publicado: (2011)

Lineage plasticity-mediated therapy resistance in prostate cancer
por: Blee, Alexandra M, et al.
Publicado: (2019)

Cell fate determination and lineage plasticity in prostate cancer
por: Gao, Dong
Publicado: (2023)

Deciphering Evolutionary Dynamics and Lineage Plasticity in Aggressive Prostate Cancer
por: Kyprianou, Natasha, et al.
Publicado: (2021)

The Role of Epigenetic Change in Therapy-Induced Neuroendocrine Prostate Cancer Lineage Plasticity
por: Storck, William K., et al.
Publicado: (2022)

An integrative modeling framework reveals plasticity of TGF-β signaling
por: Andrieux, Geoffroy, et al.
Publicado: (2014)

TGFβ signaling networks in ovarian cancer progression and plasticity
por: Kumari, Asha, et al.
Publicado: (2021)

Harnessing Carcinoma Cell Plasticity Mediated by TGF-β Signaling
por: Wang, Xuecong, et al.
Publicado: (2021)

PKR induces TGF-β and limits oncolytic immune therapy
por: Hong, Bangxing, et al.
Publicado: (2023)

Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity
por: Cyrta, Joanna, et al.
Publicado: (2020)

A key role for TGF-β1 in hippocampal synaptic plasticity and memory
por: Caraci, Filippo, et al.
Publicado: (2015)

Lineage plasticity and treatment resistance in prostate cancer: the intersection of genetics, epigenetics, and evolution
por: Imamura, Jarrell, et al.
Publicado: (2023)

Fatty Acid Signaling Impacts Prostate Cancer Lineage Plasticity in an Autocrine and Paracrine Manner
por: Zhang, Le, et al.
Publicado: (2022)

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
por: Park, Sun-Mi, et al.
Publicado: (2014)

CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition
por: Galland, Ava, et al.
Publicado: (2021)

TGF-β mediated DNA methylation in prostate cancer
por: Lee, Chung, et al.
Publicado: (2012)

Mechanisms navigating the TGF-β pathway in prostate cancer
por: Cao, Zheng, et al.
Publicado: (2015)

Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation
por: Fueyo, Raquel, et al.
Publicado: (2018)

MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
por: Yasumizu, Yota, et al.
Publicado: (2020)

Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity
por: Monga, Jitender, et al.
Publicado: (2021)

Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis
por: Han, Hyunho, et al.
Publicado: (2022)

Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration
por: Oda, Yuko, et al.
Publicado: (2020)

Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling
por: Wu, Josephine Y., et al.
Publicado: (2023)

Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling
por: Thapa, Dinesh, et al.
Publicado: (2020)

TGF-β Signaling in Neuronal Stem Cells
por: Yun, Chohee, et al.
Publicado: (2008)

Opposing roles of TGFβ and BMP signaling in prostate cancer development
por: Lu, Xin, et al.
Publicado: (2017)

A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity
por: Merrill, Jacqueline C., et al.
Publicado: (2010)

TGF-β Signaling: A Therapeutic Target to Reinstate Regenerative Plasticity in Vascular Dementia?
por: Kandasamy, Mahesh, et al.
Publicado: (2020)

FLT3 in lineage specification and plasticity
por: Greenblatt, Sarah, et al.
Publicado: (2012)

Lineage selection and plasticity in the intestinal crypt
por: Philpott, Anna, et al.
Publicado: (2014)

Stromal TGF-β signaling induces AR activation in prostate cancer
por: Yang, Feng, et al.
Publicado: (2014)

TGF-β and TGF-β/Smad Signaling in the Interactions between Echinococcus multilocularis and Its Hosts
por: Wang, Junhua, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_o64kffbeubrns6abttub54t7j9