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Polylysine is a Proteostasis Network-Engaging Structural Determinant

[Image: see text] C-terminal polylysine (PL) can be synthesized from the polyadenine tail of prematurely cleaved mRNAs or when a read-though of a stop codon happens. Due to the highly positive charge, PL stalls in the electrostatically negative ribosomal exit channel. The stalled polypeptide recruit...

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Detalles Bibliográficos
Autores principales:	Lang, Wei-Han, Calloni, Giulia, Vabulas, R. Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983878/ https://www.ncbi.nlm.nih.gov/pubmed/29634277 http://dx.doi.org/10.1021/acs.jproteome.8b00108

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