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β Cell GLP-1R Signaling Alters α Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice
Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes high rates of type 2 diabetes remission and remarkable increases in postprandial glucagon-like peptide-1 (GLP-1) secretion. GLP-1 plays a critical role in islet function by potentiating glucose-stimulated insulin secretion; however...
Autores principales: | Garibay, Darline, Lou, Jon, Lee, Seon A., Zaborska, Karolina E., Weissman, Margot H., Sloma, Erica, Donahue, Leanne, Miller, Andrew D., White, Andrew C., Michael, M. Dodson, Sloop, Kyle W., Cummings, Bethany P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983903/ https://www.ncbi.nlm.nih.gov/pubmed/29694904 http://dx.doi.org/10.1016/j.celrep.2018.03.120 |
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