Cargando…

Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF-β1/Smad3 signaling pathway

The present study aimed to assess the protective effect of epigallocatechingallate (EGCG) against myocardial injury in a mouse model of heart failure and to determine the mechanism underlying regulation of the transforming growth factor-β1/mothers against decapentaplegic homolog 3 (TGF-β1/Smad3) sig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Keyan, Chen, Wei, Liu, Shi Li, Wu, Tian Shi, Yu, Kai Feng, Qi, Jing, Wang, Yijun, Yao, Hui, Huang, Xiao Yang, Han, Ying, Hou, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983962/ https://www.ncbi.nlm.nih.gov/pubmed/29620209 http://dx.doi.org/10.3892/mmr.2018.8825

Ejemplares similares

Dapagliflozin Attenuates Myocardial Fibrosis by Inhibiting the TGF-β1/Smad Signaling Pathway in a Normoglycemic Rabbit Model of Chronic Heart Failure
por: Chen, Xuefeng, et al.
Publicado: (2022)

Cardioprotection against Heart Failure by Shenfu Injection via TGF-β/Smads Signaling Pathway
por: Ni, Jingyu, et al.
Publicado: (2017)

2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Diabetic Mice Via the TGF-β1/Smad Pathway
por: Chen, Zhengjie, et al.
Publicado: (2022)

Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β–Smad3 Pathway
por: Wang, Yinhui, et al.
Publicado: (2021)

MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1
por: Feng, Yu, et al.
Publicado: (2022)

miR-127 accelerates myocardial failure by promoting TGF-β1/Smad3 signaling
por: Xu, Hainian, et al.
Publicado: (2019)

miR-127 aggravates myocardial failure by promoting the TGF-β1/Smad3 signaling
por: Xu, Hainian, et al.
Publicado: (2018)

Losartan Attenuates Myocardial Endothelial-To-Mesenchymal Transition in Spontaneous Hypertensive Rats via Inhibiting TGF-β/Smad Signaling
por: Wu, Miao, et al.
Publicado: (2016)

Suppression of TGF-β(1)/Smad Signaling Pathway by Sesamin Contributes to the Attenuation of Myocardial Fibrosis in Spontaneously Hypertensive Rats
por: Zhao, Mengqiu, et al.
Publicado: (2015)

Inhibition of Wilms' Tumor Proliferation and Invasion by Blocking TGF-β Receptor I in the TGF-β/Smad Signaling Pathway
por: Shi, Qinlin, et al.
Publicado: (2020)

TNAP inhibition attenuates cardiac fibrosis induced by myocardial infarction through deactivating TGF-β1/Smads and activating P53 signaling pathways
por: Gao, Lei, et al.
Publicado: (2020)

Acupuncture attenuates renal interstitial fibrosis via the TGF-β/Smad pathway
por: Zuo, Zheng, et al.
Publicado: (2019)

Aspirin attenuates liver fibrosis by suppressing TGF-β1/Smad signaling
por: Sun, Yimin, et al.
Publicado: (2022)

Protein phosphatase PPM1A inhibition attenuates osteoarthritis via regulating TGF-β/Smad2 signaling in chondrocytes
por: Ge, Qinwen, et al.
Publicado: (2023)

Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model
por: Zhang, Lei, et al.
Publicado: (2017)

SMOC2 plays a role in heart failure via regulating TGF-β1/Smad3 pathway-mediated autophagy
por: Ren, Yu, et al.
Publicado: (2023)

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway
por: Li, Yali, et al.
Publicado: (2022)

Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signaling
por: Song, Yu, et al.
Publicado: (2023)

Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure
por: Humeres, Claudio, et al.
Publicado: (2022)

Liuwei Dihuang Pill Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis via TGF-β/Smad2/3 Pathway
por: Shu, Shi, et al.
Publicado: (2022)

Spatio-Temporal Distribution of Smads and Role of Smads/TGF-β/BMP-4 in the Regulation of Mouse Bladder Organogenesis
por: Islam, Syed S., et al.
Publicado: (2013)

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway
por: Mu, Mao, et al.
Publicado: (2018)

Liquiritigenin attenuates isoprenaline-induced myocardial fibrosis in mice through the TGF-β1/Smad2 and AKT/ERK signaling pathways
por: Li, Li, et al.
Publicado: (2021)

Quercetin prevents myocardial infarction adverse remodeling in rats by attenuating TGF-β1/Smad3 signaling: Different mechanisms of action
por: Albadrani, Ghadeer M., et al.
Publicado: (2021)

α1A Adrenoreceptor blockade attenuates myocardial infarction by modulating the integrin-linked kinase/TGF-β/Smad signaling pathways
por: Alrasheed, Nawal M., et al.
Publicado: (2023)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Leonurine inhibits cardiomyocyte pyroptosis to attenuate cardiac fibrosis via the TGF-β/Smad2 signalling pathway
por: Li, Zhaoyi, et al.
Publicado: (2022)

Antibacterial activities of green tea crude extracts and synergistic effects of epigallocatechingallate (EGCG) with gentamicin against MDR pathogens
por: Parvez, Md. Anowar Khasru, et al.
Publicado: (2019)

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway [Corrigendum]
por: Mu, Mao, et al.
Publicado: (2019)

Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages
por: Cui, Wei, et al.
Publicado: (2015)

Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation
por: Wang, Ruichen, et al.
Publicado: (2021)

Catalpol Attenuates Pulmonary Fibrosis by Inhibiting Ang II/AT(1) and TGF-β/Smad-Mediated Epithelial Mesenchymal Transition
por: Yu, Qun, et al.
Publicado: (2022)

Petchiether A attenuates obstructive nephropathy by suppressing TGF‐β/Smad3 and NF‐κB signalling
por: You, Yong‐Ke, et al.
Publicado: (2019)

Smad7-overexpressing rat BMSCs inhibit the fibrosis of hepatic stellate cells by regulating the TGF-β1/Smad signaling pathway
por: Wu, Shi-Pin, et al.
Publicado: (2017)

The role of TGFβ-HGF-Smad4 axis in regulating the proliferation of mouse airway progenitor cells
por: Li, Xue, et al.
Publicado: (2017)

Dual Targeted Therapy with p53 siRNA and Epigallocatechingallate in a Triple Negative Breast Cancer Cell Model
por: Braicu, Cornelia, et al.
Publicado: (2015)

(−)-Epigallocatechingallate induces apoptosis in B lymphoma cells via caspase-dependent pathway and Bcl-2 family protein modulation
por: WANG, JIANGYAN, et al.
Publicado: (2015)

Epigallocatechingallate Inhibits Migration of Human Uveal Melanoma Cells via Downregulation of Matrix Metalloproteinase-2 Activity and ERK1/2 Pathway
por: Chang, Chi-Wu, et al.
Publicado: (2014)

Smad4-mediated TGF-β signaling in tumorigenesis
por: Yang, Guan, et al.
Publicado: (2010)

The regulation of TGF-β/SMAD signaling by protein deubiquitination
por: Zhang, Juan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bd74m6h3dbo0qk9bn8vujg6p3g