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Role of cantharidin in the activation of IKKα/IκBα/NF-κB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines

Cantharidin (CAN), a potent inhibitor of serine/threonine-protein phosphatase 2A (PP2A), is widely used in clinical practice, particularly in the treatment of advanced cancer due to its specific action on these types of cancer. In the present study, the inhibitory effect of CAN was examined in two c...

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Detalles Bibliográficos
Autores principales: Zhou, Huijiang, Xu, Jiangfeng, Wang, Shuai, Peng, Jinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983964/
https://www.ncbi.nlm.nih.gov/pubmed/29620225
http://dx.doi.org/10.3892/mmr.2018.8860