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Transcriptional Profiling of Mesenchymal Stem Cells Identifies Distinct Neuroimmune Pathways Altered by CNS Disease

BACKGROUND AND OBJECTIVES: Bone marrow mesenchymal stem cells (BM-MSCs) are an attractive cell based therapy in the treatment of CNS demyelinating diseases such as multiple sclerosis (MS). Preclinical studies demonstrate that BM-MSCs can effectively reduce clinical burden and enhance recovery in exp...

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Detalles Bibliográficos
Autores principales: Sargent, Alex, Shano, Genevieve, Karl, Molly, Garrison, Eric, Miller, Christian, Miller, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984058/
https://www.ncbi.nlm.nih.gov/pubmed/29699382
http://dx.doi.org/10.15283/ijsc17062