Re-randomization increased recruitment and provided similar treatment estimates as parallel designs in trials of febrile neutropenia

OBJECTIVE: Re-randomization trials allow patients to be re-enrolled for multiple treatment episodes. However, it remains uncertain to what extent re-randomization improves recruitment compared to parallel group designs or whether treatment estimates might be affected. STUDY DESIGN AND SETTING: We ev...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C., Morris, Tim P., Harris, Erica, Pearse, Rupert, Hooper, Richard, Eldridge, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984235/
https://www.ncbi.nlm.nih.gov/pubmed/29428873
http://dx.doi.org/10.1016/j.jclinepi.2018.02.002

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