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ERK is a negative feedback regulator for IFN-γ/STAT1 signaling by promoting STAT1 ubiquitination

BACKGROUND: We recently reported that STAT1 plays a tumor suppressor role, and ERK was inversely correlation with STAT1 expression in esophageal squamous cell carcinoma (ESCC). Here, we investigated the mechanism(s) that are responsible for the ERK regulates STAT1 in ESCC. METHODS: We performed the...

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Detalles Bibliográficos
Autores principales:	Zhang, Ying, Chen, Yelong, Liu, Zhaoyong, Lai, Raymond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984314/ https://www.ncbi.nlm.nih.gov/pubmed/29855346 http://dx.doi.org/10.1186/s12885-018-4539-7

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