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HIF-1α promotes the migration and invasion of hepatocellular carcinoma cells via the IL-8–NF-κB axis
BACKGROUND: Hypoxia plays a critical role in many cancers. Hypoxia inducible factor-1α (HIF-1α) is an important mediator of the hypoxia response. It regulates the expression of various chemokines involved in tumor growth, angiogenesis and metastasis but the associated pathway needs further investiga...
Autores principales: | Feng, Wenming, Xue, Tao, Huang, Sanxiong, Shi, Qilin, Tang, Chengwu, Cui, Ge, Yang, Guanghui, Gong, Hui, Guo, Huihui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984319/ https://www.ncbi.nlm.nih.gov/pubmed/29881400 http://dx.doi.org/10.1186/s11658-018-0077-1 |
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