Cargando…

An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae

BACKGROUND: The ideal biofuel should not only be a regenerative fuel from renewable feedstocks, but should also be compatible with the existing fuel distribution infrastructure and with normal car engines. As the so-called drop-in biofuel, the fatty alcohol 1-octanol has been described as a valuable...

Descripción completa

Detalles Bibliográficos
Autores principales:	Henritzi, Sandra, Fischer, Manuel, Grininger, Martin, Oreb, Mislav, Boles, Eckhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984327/ https://www.ncbi.nlm.nih.gov/pubmed/29881455 http://dx.doi.org/10.1186/s13068-018-1149-1

Ejemplares similares

De novo biosynthesis of 8-hydroxyoctanoic acid via a medium-chain length specific fatty acid synthase and cytochrome P450 in Saccharomyces cerevisiae
por: Wernig, Florian, et al.
Publicado: (2019)

Fusing α and β subunits of the fungal fatty acid synthase leads to improved production of fatty acids
por: Wernig, Florian, et al.
Publicado: (2020)

Transcriptomic response of Saccharomyces cerevisiae to octanoic acid production
por: Baumann, Leonie, et al.
Publicado: (2021)

Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transporters
por: Jordan, Paulina, et al.
Publicado: (2016)

De novo production of aromatic m-cresol in Saccharomyces cerevisiae mediated by heterologous polyketide synthases combined with a 6-methylsalicylic acid decarboxylase
por: Hitschler, Julia, et al.
Publicado: (2019)

Identification of a glucose-insensitive variant of Gal2 from Saccharomyces cerevisiae exhibiting a high pentose transport capacity
por: Rojas, Sebastian A. Tamayo, et al.
Publicado: (2021)

Engineering cofactor supply and NADH-dependent d-galacturonic acid reductases for redox-balanced production of l-galactonate in Saccharomyces cerevisiae
por: Harth, Simon, et al.
Publicado: (2020)

Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
por: Gajewski, Jan, et al.
Publicado: (2017)

Subcellular Localization of Fad1p in Saccharomyces cerevisiae: A Choice at Post-Transcriptional Level?
por: Bruni, Francesco, et al.
Publicado: (2021)

Bacterial bifunctional chorismate mutase-prephenate dehydratase PheA increases flux into the yeast phenylalanine pathway and improves mandelic acid production
por: Reifenrath, Mara, et al.
Publicado: (2018)

Substrate promiscuity of polyketide synthase enables production of tsetse fly attractants 3-ethylphenol and 3-propylphenol by engineering precursor supply in yeast
por: Hitschler, Julia, et al.
Publicado: (2020)

Novel strategies to improve co-fermentation of pentoses with D-glucose by recombinant yeast strains in lignocellulosic hydrolysates
por: Oreb, Mislav, et al.
Publicado: (2012)

Increasing n-butanol production with Saccharomyces cerevisiae by optimizing acetyl-CoA synthesis, NADH levels and trans-2-enoyl-CoA reductase expression
por: Schadeweg, Virginia, et al.
Publicado: (2016)

An optimized reverse β-oxidation pathway to produce selected medium-chain fatty acids in Saccharomyces cerevisiae
por: Garces Daza, Fernando, et al.
Publicado: (2023)

Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae
por: Brat, Dawid, et al.
Publicado: (2012)

Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae
por: Subtil, Thorsten, et al.
Publicado: (2012)

Strategies in megasynthase engineering – fatty acid synthases (FAS) as model proteins
por: Fischer, Manuel, et al.
Publicado: (2017)

n-Butanol production in Saccharomyces cerevisiae is limited by the availability of coenzyme A and cytosolic acetyl-CoA
por: Schadeweg, Virginia, et al.
Publicado: (2016)

Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae
por: Berg, Matthew D., et al.
Publicado: (2020)

Amino Acid Transporter Genes Are Essential for FLO11-Dependent and FLO11-Independent Biofilm Formation and Invasive Growth in Saccharomyces cerevisiae
por: Torbensen, Rasmus, et al.
Publicado: (2012)

Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators
por: Tripp, Joanna, et al.
Publicado: (2017)

Identification of the Aldo-Keto Reductase Responsible for d-Galacturonic Acid Conversion to l-Galactonate in Saccharomyces cerevisiae
por: Rippert, Dorthe, et al.
Publicado: (2021)

Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters
por: Subtil, Thorsten, et al.
Publicado: (2011)

De novo biosynthesis of liquiritin in Saccharomyces cerevisiae
por: Yin, Yan, et al.
Publicado: (2020)

Industrial Systems Biology of Saccharomyces cerevisiae Enables Novel Succinic Acid Cell Factory
por: Otero, José Manuel, et al.
Publicado: (2013)

Improving isobutanol production with the yeast Saccharomyces cerevisiae by successively blocking competing metabolic pathways as well as ethanol and glycerol formation
por: Wess, Johannes, et al.
Publicado: (2019)

Co-utilization of L-arabinose and D-xylose by laboratory and industrial Saccharomyces cerevisiae strains
por: Karhumaa, Kaisa, et al.
Publicado: (2006)

Optimization of a hybrid bacterial/Arabidopsis thaliana fatty acid synthase system II in Saccharomyces cerevisiae
por: Pozdniakova, Tatiana A., et al.
Publicado: (2023)

Whole‐cell biocatalytic and de novo production of alkanes from free fatty acids in Saccharomyces cerevisiae
por: Foo, Jee Loon, et al.
Publicado: (2016)

De Novo Production of Glycyrrhetic Acid 3-O-mono-β-D-glucuronide in Saccharomyces cerevisiae
por: Huang, Ying, et al.
Publicado: (2021)

The introduction of the fungal d-galacturonate pathway enables the consumption of d-galacturonic acid by Saccharomyces cerevisiae
por: Biz, Alessandra, et al.
Publicado: (2016)

Heterologous production of levopimaric acid in Saccharomyces cerevisiae
por: Liu, Ting, et al.
Publicado: (2018)

Growth Inhibition by Amino Acids in Saccharomyces cerevisiae
por: Ruiz, Stephanie J., et al.
Publicado: (2020)

Engineering de novo anthocyanin production in Saccharomyces cerevisiae
por: Levisson, Mark, et al.
Publicado: (2018)

Engineered Saccharomyces cerevisiae for the De Novo Biosynthesis of (−)-Menthol
por: Lv, Xueqin, et al.
Publicado: (2022)

De Novo Biosynthesis of Vindoline and Catharanthine in Saccharomyces cerevisiae
por: Gao, Di, et al.
Publicado: (2022)

On the Role of the Carboxyl Group to the Protective Effect of o-dihydroxybenzoic Acids to Saccharomyces cerevisiae Cells upon Induced Oxidative Stress
por: Nenadis, Nikolaos, et al.
Publicado: (2022)

Type I fatty acid synthase trapped in the octanoyl‐bound state
por: Rittner, Alexander, et al.
Publicado: (2020)

Regulators of ribonucleotide reductase inhibit Ty1 mobility in saccharomyces cerevisiae
por: O'Donnell, John P, et al.
Publicado: (2010)

Characterization of Carboxylic Acid Reductases as Enzymes in the Toolbox for Synthetic Chemistry
por: Finnigan, William, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1698dhdbq0ft3fvnopve4dbaok