The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) has, in recent years, emerged as an important tumor cell behavior associated with high metastatic potential and drug resistance. Interestingly, protein SUMOylation and hepatocyte growth factor could respectively reduce the effect of small molecu...

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Detalles Bibliográficos
Autores principales: Joseph, Nithila A., Chiou, Shiow-Her, Lung, Zoe, Yang, Cheng-Lin, Lin, Tze-Yi, Chang, Hui-Wen, Sun, H. Sunny, Gupta, Sachin Kumar, Yen, Laising, Wang, Shulhn-Der, Chow, Kuan-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984410/
https://www.ncbi.nlm.nih.gov/pubmed/29855336
http://dx.doi.org/10.1186/s13045-018-0557-9

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