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The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer

This study investigated the effect of radiofrequency hyperthermia combined with chemotherapy in the treatment of advanced ovarian cancer. METHODS: Seventy-five patients with advanced ovarian cancer were grouped into observation (n = 36) and control (n = 37) groups according to different treatment me...

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Autores principales: Li, Zhihui, Sun, Qinge, Huang, Xiaoyan, Zhang, Jianzhong, Hao, Jing, Li, Yue, Zhang, Shihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984478/
https://www.ncbi.nlm.nih.gov/pubmed/29876524
http://dx.doi.org/10.1515/med-2018-0013
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author Li, Zhihui
Sun, Qinge
Huang, Xiaoyan
Zhang, Jianzhong
Hao, Jing
Li, Yue
Zhang, Shihong
author_facet Li, Zhihui
Sun, Qinge
Huang, Xiaoyan
Zhang, Jianzhong
Hao, Jing
Li, Yue
Zhang, Shihong
author_sort Li, Zhihui
collection PubMed
description This study investigated the effect of radiofrequency hyperthermia combined with chemotherapy in the treatment of advanced ovarian cancer. METHODS: Seventy-five patients with advanced ovarian cancer were grouped into observation (n = 36) and control (n = 37) groups according to different treatment methods. The age of the patients in the control and the experimental groups were (55 + 11) and (53 + 12) years old, respectively. The control group was received chemotherapy alone (paclitaxel + cisplatin chemotherapy), and on the basis of systemic chemotherapy, the observation group was administered therapy in conjunction with abdominal pelvic radiofrequency hyperthermia. RESULTS: The tumor remission rate, ascites, serum CA125 levels, pain control, quality of life enhancement, III+IV bone marrow suppression and improvement of gastrointestinal reaction in the observation group were better than those of the control group (all P< 0.05). CONCLUSION: Radiofrequency hyperthermia combined with chemotherapy in the treatment of advanced ovarian cancer has significantly improved the tumor remission rate, ascite control and CA125 levels, and substantially reduced the gastrointestinal reaction and bone marrow suppression rate, which is worthy of intensive clinical application.
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spelling pubmed-59844782018-06-06 The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer Li, Zhihui Sun, Qinge Huang, Xiaoyan Zhang, Jianzhong Hao, Jing Li, Yue Zhang, Shihong Open Med (Wars) Regular Articles This study investigated the effect of radiofrequency hyperthermia combined with chemotherapy in the treatment of advanced ovarian cancer. METHODS: Seventy-five patients with advanced ovarian cancer were grouped into observation (n = 36) and control (n = 37) groups according to different treatment methods. The age of the patients in the control and the experimental groups were (55 + 11) and (53 + 12) years old, respectively. The control group was received chemotherapy alone (paclitaxel + cisplatin chemotherapy), and on the basis of systemic chemotherapy, the observation group was administered therapy in conjunction with abdominal pelvic radiofrequency hyperthermia. RESULTS: The tumor remission rate, ascites, serum CA125 levels, pain control, quality of life enhancement, III+IV bone marrow suppression and improvement of gastrointestinal reaction in the observation group were better than those of the control group (all P< 0.05). CONCLUSION: Radiofrequency hyperthermia combined with chemotherapy in the treatment of advanced ovarian cancer has significantly improved the tumor remission rate, ascite control and CA125 levels, and substantially reduced the gastrointestinal reaction and bone marrow suppression rate, which is worthy of intensive clinical application. De Gruyter Open 2018-06-01 /pmc/articles/PMC5984478/ /pubmed/29876524 http://dx.doi.org/10.1515/med-2018-0013 Text en © 2018 Zhihui Li et al. http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
spellingShingle Regular Articles
Li, Zhihui
Sun, Qinge
Huang, Xiaoyan
Zhang, Jianzhong
Hao, Jing
Li, Yue
Zhang, Shihong
The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer
title The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer
title_full The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer
title_fullStr The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer
title_full_unstemmed The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer
title_short The Efficacy of Radiofrequency Hyperthermia Combined with Chemotherapy in the Treatment of Advanced Ovarian Cancer
title_sort efficacy of radiofrequency hyperthermia combined with chemotherapy in the treatment of advanced ovarian cancer
topic Regular Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984478/
https://www.ncbi.nlm.nih.gov/pubmed/29876524
http://dx.doi.org/10.1515/med-2018-0013
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